Science AI skills, agents & prompts

Lab work, datasets and papers — the jobs a researcher finishes. 102 listings — 100 skills and 2 prompts — each free, credited to its author, with the full source on its page. Filter and sort them →

Genomics & omics

Reads, counts and cells — from raw sequencing to a result you can defend.
AnndataData structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or…skill · MITArboretoInfer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2…skill · MITBiopython: Computational Molecular Biology in PythonComprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB)…skill · MITBulk rnaseqEnd-to-end bulk RNA-seq orchestrator — takes raw FASTQ reads through QC and trimming (FastQC, fastp/Trim…skill · MITCOBRApy - Constraint-Based Reconstruction and AnalysisConstraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for…skill · MITCZ CELLxGENE CensusQuery the CZ CELLxGENE Census programmatically for versioned public single-cell and spatial transcriptomics…skill · MITDeepspot mGenerate transcriptome-wide virtual spatial transcriptomics from H&E histology with DeepSpot-M. Use when you…skill · MITDepMap — Cancer Dependency MapQuery the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores (CRISPR Chronos), drug…skill · MITETE Toolkit 4Analyze, manipulate, compare, annotate, and visualize phylogenetic or other hierarchical trees with ETE 4…skill · MITFlowioRead, inspect, and write Flow Cytometry Standard (FCS) 2.0, 3.0, and 3.1 files with FlowIO. Use for…skill · MITFolklore variant evidenceRetrieve ClinGen gene-disease validity assertions for a public gene or disease, and review source-linked…skill · MITGenimlUse Geniml for audited local genomic-interval workflows: validate BED and universe contracts, plan…skill · MITGenomic coordinatesConvert genomic intervals between coordinate conventions, normalise and compare variant representations, and…skill · MITGgetFast CLI/Python queries to 20+ bioinformatics databases. Use for quick lookups: gene info, BLAST/BLAT, viral…skill · MITGlycoengineeringAnalyze and engineer protein glycosylation. Scan sequences for N-glycosylation sequons (N-X-S/T), predict…skill · MITHugging scienceUse when the user is doing AI/ML work in a scientific domain such as biology, chemistry, physics, astronomy…skill · MITLamindbUse when working with LaminDB, the open-source lineage-native lakehouse for biological datasets and models…skill · MITPathogen variant surveillanceQuery live pathogen genomic surveillance data through the GenSpectrum LAPIS API to find which viral lineages…skill · MITPathway enrichmentRun pathway and gene-set enrichment analysis on gene lists or ranked gene data, then interpret the results…skill · MITPhylogeneticsBuild and analyze phylogenetic trees using MAFFT (multiple alignment), IQ-TREE 2 (maximum likelihood), and…skill · MITPolars bioHigh-performance genomic interval operations and bioinformatics file I/O on Polars DataFrames. Overlap…skill · MITPydeseq2Differential gene expression analysis for bulk RNA-seq with PyDESeq2, including formulaic designs, Wald…skill · MITPysamPython/HTSlib workflows for genomic files. Use when reading, querying, filtering, or writing SAM/BAM/CRAM…skill · MITScanpy: Single-Cell AnalysisStandard single-cell RNA-seq analysis pipeline. Use for QC, normalization, dimensionality reduction…skill · MITScikit bioBiological data toolkit. Sequence analysis, alignments, phylogenetic trees, diversity metrics (alpha/beta…skill · MITscVelo — RNA Velocity AnalysisRNA velocity analysis with scVelo. Estimate cell state transitions from unspliced/spliced mRNA dynamics…skill · MITScvi toolsDeep generative models for single-cell omics. Use when you need probabilistic batch correction (scVI)…skill · MITTiledbvcfEfficient storage and retrieval of genomic variant data using TileDB. Scalable VCF/BCF ingestion…skill · MIT

Molecules & structures

Docking, folding and the shape of the thing you are studying.
Datamol Cheminformatics SkillPythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug…skill · MITDeepchemMolecular ML with diverse featurizers and pre-built datasets. Use for property prediction (ADMET, toxicity)…skill · MITDiffDock: Molecular Docking with Diffusion ModelsDiffDock and DiffDock-L molecular docking. Use for protein-small-molecule pose prediction from PDB or…skill · MITMatchmsProcess, clean, compare, and search tandem mass spectra with matchms. Use for MS/MS file I/O, metadata…skill · MITMedchemMedicinal chemistry filters for compound triage. Apply drug-likeness rules (Lipinski, Veber, CNS)…skill · MITMolecular dynamicsRun and analyze molecular dynamics simulations with OpenMM and MDAnalysis. Set up protein/small molecule…skill · MITMolfeat - Molecular Featurization HubMolecular featurization for ML (100+ featurizers). ECFP, MACCS, descriptors, pretrained models (ChemBERTa)…skill · MITPymatgenAnalyze, validate, convert, and transform materials structures and computed materials data with current…skill · MITPyopenmsComplete mass spectrometry analysis platform. Use for proteomics and metabolomics workflows—feature…skill · MITPyTDC (Therapeutics Data Commons)Use Therapeutics Data Commons through the PyTDC Python package for registry discovery, approved dataset…skill · MITRDKit Cheminformatics ToolkitCheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP…skill · MITRowan: Cloud-Native Molecular-Modeling and Drug-Design WorkflowsRowan is a cloud-native molecular modeling and medicinal-chemistry workflow platform with a Python API. Use…skill · MITTorchdrugBuild and troubleshoot TorchDrug 0.2.1 workflows for molecular graphs, property prediction, self-supervised…skill · MITUmap learnUse UMAP-learn for nonlinear dimensionality reduction, 2D/3D embeddings, clustering preprocessing…skill · MIT

Clinical & trials

Protocols, patient data and the reports regulators read.

Physics & astronomy

Signals, spectra and sky surveys.

Research data

Getting the dataset clean, documented and reusable.
Analytical method validationPlan, execute, and document validation, verification, and transfer of analytical procedures under the…skill · MITAutoskillObserve the user's screen via screenpipe, detect repeated research workflows, match them against existing…skill · MITBioservicesUnified Python interface to 40+ bioinformatics services. Use when querying multiple databases (UniProt…skill · MITDatabase lookupQuery documented public database APIs with explicit endpoints, filters, pagination, and provenance. Use when…skill · MITExperimental designDesign experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and…skill · MITGinkgo cloud labSubmit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud.ginkgo.bio), a web-based interface for…skill · MITLab hardware cadDesign custom laboratory hardware as parametric build123d models and export fabrication-ready STEP, STL, and…skill · MITLiteParse — Local Document ParsingLocal document and PDF parsing that returns spatial text with bounding boxes. Use for extracting text from…skill · MITMatplotlibLow-level plotting library for full customization. Use when you need fine-grained control over every plot…skill · MITNetworkxCreate, analyze, and visualize complex networks and graphs in Python with NetworkX. Use when working with…skill · MITOmero integrationSecurely inspect and automate microscopy data workflows against OMERO.server with omero-py, BlitzGateway…skill · MITOntology term resolutionResolve free-text scientific labels to ontology term IDs and validate existing CURIEs against the EBI…skill · MITOpen notebookSelf-hosted, open-source alternative to Google NotebookLM for AI-powered research and document analysis. Use…skill · MITOpentrons integrationAuthor, review, migrate, simulate, and troubleshoot official Opentrons Python Protocol API v2 protocols for…skill · MITParallel Web ToolkitUse Parallel CLI for web search, URL extraction, deep research, structured data enrichment, entity…skill · MITPylabrobotDevelop and review PyLabRobot lab-automation resources, liquid-handling plans, offline simulations, and…skill · MITSeaborn Statistical VisualizationStatistical visualization with pandas integration. Use for quick exploration of distributions…skill · MITShapExplain and audit machine-learning predictions with SHAP. Use for selecting SHAP explainers and maskers…skill · MITStatistical analysisGuided statistical analysis for research data - test selection, assumption checking, effect sizes, power…skill · MITTimesfm forecastingZero-shot time series forecasting with Google's TimesFM foundation model. Use for any univariate time series…skill · MITVaexUse this skill for processing and analyzing large tabular datasets (billions of rows) that exceed available…skill · MIT

Papers & citations

The literature going in, and the manuscript coming out.
Act as a senior research paper evaluatorUse this prompt to critically evaluate academic papers. Ideal for reviewers aiming to assess the quality and…prompt · CC0-1.0Bibliographic review writing assistantAssist users in drafting and reviewing bibliographic literature reviews, ensuring compliance with APA 7th…prompt · CC0-1.0Citation managementComprehensive citation management for academic research. Search OpenAlex, PubMed, and Google Scholar for…skill · MITExa Web ToolkitWeb toolkit powered by Exa, tuned for scientific and technical content. Use this skill when the user needs…skill · MITLaTeX Research PostersCreate professional research posters in LaTeX using beamerposter, tikzposter, or baposter. Support for…skill · MITLiterature reviewConduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv…skill · MITPaper lookupSearch 18 scholarly APIs for papers, preprints, citations, open-access full text, repository records, and…skill · MITPaperzillaChat with your agent about projects, recommendations, and canonical papers in Paperzilla. Use when users ask…skill · MITPeer reviewPrepare evidence-bounded, constructive peer-review drafts and structured manuscript assessments. Use for…skill · MITPyzoteroInteract with Zotero reference management libraries using the pyzotero Python client. Retrieve, create…skill · MITResearch Grant WritingWrite competitive research proposals for NSF, NIH, DOE, DARPA, and Taiwan NSTC. Agency-specific formatting…skill · MITResearch lookupCompile current scholarly evidence for a scientific manuscript or research brief. Use when the user…skill · MITScholar evaluationProvide qualitative-first, evidence-traceable developmental review of scholarly works and audit low-stakes…skill · MITScientific brainstormingFacilitates evidence-aware scientific ideation with independent generation, structured discussion, explicit…skill · MITScientific Hypothesis GenerationFormulate evidence-bounded scientific questions, candidate hypotheses, rival explanations, causal or…skill · MITScientific writingDraft, revise, and audit scientific manuscripts or reports with explicit evidence provenance…skill · MITVenue templatesPrepare journal manuscripts, conference papers, research posters, and grant documents using venue-specific…skill · MITLitreview — Academic Literature OrientationAcademic literature orientation skill that searches papers via free keyless APIs (PubMed E-utilities +…skill · MITGrant Proposal SkillWrite a structured grant proposal or funding application for any grant type. Use when asked to write a grant…skill · MITLiterature Review SkillStructure and write a literature review for any research topic. Use when asked to write a literature review…skill · MITStory maintenanceThis skill should be used when the user asks to validate, reindex, repair registries, check links, check…skill · MIT

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